CycloheximideCulturePure®isapurifiedversion(≥98%pure)ofCycloheximidethatisfreeoftoxicisomers.ItisaglutarimideantibioticandnaturalfungicideisolatedfromStreptomycesgriseusandaproteinsynthesisinhibitorineukaryoticcells.ItwasdiscoveredbyAlmaWhiffen-BarksdaleofUpjohnCompanyin1946.Itisroutinelyusedasaselectionagentinseveraltypesofisolationmedia.ItcanbeusedasatoolinmolecularBIOLOGytodeterminethehalflifeofproteins,orininchaseexperimentstoanalyzeproteindegradation.
Thisproductisconsideredadangerousgood.Quantitiesabove1gmaybesubjecttoadditionalshippingfees.Pleasecontactusfordetails.
Wealsooffer:
- Cycloheximide(C001)
- CycloheximideSolution(C071)
- CycloheximideA,EvoPure®(C123)
CASNumber
66-81-9
MolecularFormula
C15H23NO4
MolecularWeight
281.35
MechanismofAction
CycloheximidebindstotheribosomeandinhibitstheeEF2-mediatedtranslocationstepinproteinsynthesis,thusblockingtranslationalelongation.
StorageConditions
Ambient
TariffCode
2941.90.1050
Spectrum
Cycloheximideisusedforfungiandyeast,includingfungifoundinbrewingtestmedia.Ithasloweractivityagainstbacteria.
