Ertapenemsodium,EvoPure®isahighlypurifiedformofErtapenemsodium.Itisabroad-spectrumβ-lactamcarbapenemthatinterfereswithpeptidoglycansynthesis.Ertapenemsodiumissolubleinwaterandsodiumchloride.
CASNumber
153773-82-1
MolecularFormula
C22H24N3O7S•xNa(lotspecific)
MolecularWeight
474.51g/mol(Freebase)
MechanismofAction
β-lactamsinterferewithPBP(penicillinbindingprotein)activityinvolvedinthefinalphaseofpeptidoglycansynthesis.PBP’sareenzymeswhichcatalyzeapentaglycinecrosslinkbetweenalanineandlysineresiduesprovidingadditionalstrengthtothecellwall.Withoutapentaglycinecrosslink,theintegrityofthecellwallisseverelycompromisedandultimatelyleadstocelllysisanddeath.Resistancetoβ-lactamsiscommonlyduetocellscontainingplasmidencodedβ-lactamases.
StorageConditions
-20°C
TariffCode
2941.90.3000
Spectrum
Ertapenemsodiumhasbroad-spectrumactivitytargetingawidespectrumofaerobicandanaerobicGram-positiveandGram-negativebacteria.