Cycloheximide A, EvoPure® is a highly purified (≥99.0) form of Cycloheximide A, the active compound in standard grade cycloheximide. Cycloheximide is a glutarimide antibiotic and natural fungicide isolated from Streptomyces griseus and a protein synthesis inhibitor in eukaryotic cells. It was discovered by Alma Whiffen-Barksdale of Upjohn Company in 1946. It is routinely used as a selection agent in several types of isolation media. It can be used as a tool in molecular biology to determine the half life of proteins, or in in chase experiments to analyze protein degradation.
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We also offer:
- Cycloheximide (C001)
- Cycloheximide Solution (C084)
- Cycloheximide, CulturePure® (C071)
CAS Number
66-81-9
Molecular Formula
C15H23NO4
Molecular Weight
281.35
Mechanism of Action
Cycloheximide binds to the ribosome and inhibits the eEF2-mediated translocation step in protein synthesis, thus blocking translational elongation.
Storage Conditions
-20°C
Tariff Code
2941.90.1050
Spectrum
Cycloheximide is used for fungi and yeast, including fungi found in brewing test media.It has lower activity against bacteria.
