Kanamycin, USP is an aminoglycoside antibiotic often used to select for bacteria which have been successfully transformed with a plasmid conferring kanamycin resistance.
Standard grade kanamycin is composed of a mixture of three different fractions: Kanamycin A, B, and C. TOKU-E offers five forms of kanamycin:
- Kanamycin sulfate
- Kanamycin acid sulfate (both BP grade and EP grade)
- Kanamycin A sulfate, EvoPure®
- Kanamycin B sulfate, EvoPure®
EvoPure® products are purified single antibiotic fractions, most >99% pure. High purityEvoPure®kanamycin products can be used to analyze the specific effects of individual kanamycin fractions.
CAS Number
133-92-6; 25389-94-0
Molecular Formula
C18H36N4O11 · H2SO4
Molecular Weight
582.58 g/mol
Mechanism of Action
Aminoglycosides target the 30S ribosomal subunit resulting in an inability to read mRNA ultimately producing a faulty or nonexistent protein.Kanamycin is very soluble in aqueous solution at 92.3 mg/mL.
Storage Conditions
Stock solutions should be stored at 2-8 °C.
Tariff Code
2941.90.1010
Spectrum
Kanamycin sulfate is a broad spectrum antibiotic but is most active against aerobic Gram-negative bacteria.
