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Powder
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Whiteoroff-whitecrystallinepowder
Source
Streptomycesverticillus 4.5-6.0 ≤6.0%pH
LossonDrying
BleomycinA2sulfateisoneoftwocomponentsfoundintheglycopeptideantibioticbleomycinsulfate,achemotherapeuticagentusedforthetreatmentofHodgkin"slymphoma.BleomycinA2andB2arestructurallysimilaranddifferbyauniqueterminalaminegroup.
TOKU-Eoffersthreeformsofbleomycin:bleomycinsulfate(B005),bleomycinA2sulfate,EvoPure®(B019),andbleomycinB2sulfate,EvoPure®(B020).EvoPure®productsareindividualmolecularfractions,most>99%pure.
11116-31-7
C55H84N17O21S3·xH2SO4(lotspecific)
1415.55(Freebase)
BleomycinactsasananticanceragentbycausingsinglestrandedbreaksinDNA.Theexactmechanismisnotwelldefinedhowever;itisthoughttochelatemetallicionstodecreaseenzymeactivityandstABIlity.ThiseffectisbelievedtocauseenzymestoreactwithoxygenproducingfreerADIcalswhichcreatesinglestrandedbreaksindeoxyribosesugar.
-20°C
2941.90.5000
Powder
Whiteoroff-whitecrystallinepowder
Streptomycesverticillus 4.5-6.0 ≤6.0%pH
LossonDrying