Form
Powder
Appearance
Whitecrystalpowder
Source
TolypoclADIumInflatum
WaterContent(KarlFisher)
3.0%
MeltingPoint
162-165°C
Assay
≥95.0%
HeavyMetals
≤0.02%
Impurities
Total:≤5.0%
CyclosporinHisahydroxylatedmetaboliteofcyclosporinA(CsA).CyclosporinH(M-1)andothercyclosporinmetaboliteshavebeenfoundtohavelower(<10%)immunosuppressantactivitythancyclosporinA(CsA).CyclosporinHhasbeenfoundtobeapotentinhibitorofsuperoxideanion(O2-)formationbyFMLP(N-Formylmethionyl-leucyl-phenylalanine)inhumanneutrophils.
Formorecyclosporinproducts,clickhere.
83602-39-5
C62H111N11O12
1202.6g/mol
CyclosporinH(andothercyclosporinA(CsA)metabolites)havelowerimmunosuppressantactivitybutmostlikelyoperateunderthesamemechanismascyclosporinA(CsA)describedbelow.
-20°C
2933.79.8500
Powder
Whitecrystalpowder
TolypoclADIumInflatum
3.0%
162-165°C
≥95.0%
≤0.02%
Total:≤5.0%