Appearance
Beigeorwhitepowder
Source
BacillusSubtilisvarTracy
WaterContent(KarlFisher)
reported
Assay
>90%(HPLC)
Bacitraciniscomprisedofnumerousantimicrobialpeptidefractions.NotablefractionsincludeA,A1,B,B1,B2,C,D,E,F,G,andX.Standardgradebacitracin(B002)isamixtureofthesefractions.BacitracinAisthemostactiveandpotentpeptidefractioninbacitracinandisverysimilartoitsbacitracinBcounterpart.
Formorebacitracinproducts,includingfractions, clickhere.
N/A
C65H101N17O16S
1408.69g/mol
Bacitracinpreventsphosphorylationofbactoprenol;atransportproteinwhichcarriespeptidoglycancomponentsoutsidethecellmembrane.Withouttheactivephosphorylatedbactoprenol,peptidoglycansynthesiscannotbecompleteandthecelllyses.Twomechanismsofbacitracinresistanceareunderstood.OnemechanismreliesonaproteincalledaBcrABCtransporterwhichpumpsbacitracinoutafterithasenteredthecell.AnalternativemechanismisduetoanotherproteincalledBacAwhichprovidestheactivephosphorylatedbactoprenolfromadifferentsyntheticpathway.
-20°C
2941.90.5000
BacitracinprimarilytargetsthecellwallinmembersofthegrampositivebacteriaincludingStreptococcuspyogenesandStaphylococcusaureus.
Beigeorwhitepowder
BacillusSubtilisvarTracy
reported
>90%(HPLC)