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Whiteoralmostwhitepowder
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BacillussubtitlisvarTracy
WaterContent(KarlFisher)
Reported
Assay
>90%(HPLC)
Bacitraciniscomprisedofnumerousantimicrobialpeptidefractions.NotablefractionsincludeA,A1,B,B1,B2,C,D,E,F,G,andX.Standardgradebacitracin(B002)isamixtureofthesefractions.BacitracinAisthemostactiveandpotentpeptidefractioninbacitracinandisverysimilartoitsbacitracinBcounterpart.
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57762-79-5
C65H101N17O16S
1408.66g/mol
Bacitracinpreventsphosphorylationofbactoprenol;atransportproteinwhichcarriespeptidoglycancomponentsoutsidethecellmembrane.Withouttheactivephosphorylatedbactoprenol,peptidoglycansynthesiscannotbecompleteandthecelllyses.Twomechanismsofbacitracinresistanceareunderstood.OnemechanismreliesonaproteincalledaBcrABCtransporterwhichpumpsbacitracinoutafterithasenteredthecell.AnalternativemechanismisduetoanotherproteincalledBacAwhichprovidestheactivephosphorylatedbactoprenolfromadifferentsyntheticpathway.
-20°C
2941.90.5000
BacitracinprimarilytargetsthecellwallinmembersofthegrampositivebacteriaincludingStreptococcuspyogenesandStaphylococcusaureus.
Powder
Whiteoralmostwhitepowder
BacillussubtitlisvarTracy
Reported
>90%(HPLC)