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Enramycin(alsoknownasEnduracidinandEnrADIn)isapolypeptideantibiotic producedby Streptomycesfungicidusand developedasafoodadditiveinJapan.EnramycinisslightlysolubleinwaterandfreelysolubleindiluteHClsolution.Enramyciniscomposedoftwodifferentcompounds:enramycinAandenramycinB.
TOKU-Eoffersthreeformsofenramycin:enramycin(E006),enramycinA,EvoPure®(E018),andenramycinB,EvoPure®(E019).EvoPure®productsaresingleantibioticfractions,most>99%pure.
34438-27-2
C107H138CI2N26O31
2355.30
EnramycinactsasaMurGinhibitorinvolvedpeptidoglycansynthesisingrampositivebacteria.MurGcatalyzesthetransglycosylationreactioninthelaststepofpeptidoglycanbiosynthesis.Inhibitionofthisstepgreatlycompromisescellwallintegrityleadingtocelldeathbylysis.
-20°C
2941.90.1050
EnramycinhasastrongantibacterialactivityagainstGram-positivebacteriaandinhibitsdevelopmentofmajorgutflorapathogens. Resistanceorcross-resistancewithexistingantibioticshasrarelybeenobserved.
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