Artesunate is an anti-malarial drug and has been found to be effective against multidrug-resistant
malaria. Artesunate has also been found to have anti-cancer activity against leukemia and colon cancer cell lines.
CAS Number
88495-63-0
Molecular Formula
C19H28O8
Molecular Weight
384.42
Mechanism of Action
Artesunate causes double stranded breaks in parasite DNA which leads to a buildup of intracellular reactive oxygen species (ROS).
Storage Conditions
≤30°C
Spectrum
Artesunate is active against Plasmodium falciparum and P. vivax.
Form
Powder
Appearance
White crystalline powder
Source
Artemisia annua
Impurity Profile
Single impurity: Not more than 0.5%
Total impurities: Not more than 2.0%
pH
3.5 - 5.0
Melting Point
132°C - 136°C
Optical Rotation
+4.5 - +6.5
Assay
(HPLC, On dried basis): 98.0% - 102.0%
Loss on Drying
Not more than 0.5%
Residue On Ignition
Not more than 0.1%
Heavy Metals
Not more than 20ppm
