Form
Powder
Appearance
Whiteoroff-whitepowder
Source
Synthetic
MeltingPoint
223-228°C
Assay
98.0-101.0%
LossonDrying
≤0.5%
Erlotinibhydrochlorideisadrugusedtotreatnon-smallcelllungcancer,pancreaticcancerandseveralothertypesofcancer.Itisatyrosinekinaseinhibitor,whichactsontheepidermalgrowthfactorreceptor(EGFR).
183319-69-9
C22H23N3O4
393.43
Erlotinibisanepidermalgrowthfactorreceptor(EGFR)inhibitor.ErlotinibspecificallytargetstheEGFRtyrosinekinaseATPbindingsite,whichishighlyexpressedandoccasionallymutatedinvariousformsofcancer.ErlotinibpreventsEGFRhomodimerformation,aconformationalchangerequiredforsignaltransmittance.
2-8°C
2933.59.5300
Powder
Whiteoroff-whitepowder
Synthetic
223-228°C
98.0-101.0%
≤0.5%