Source
Camptotheca acuminata (plant)
Impurity Profile
RRT1.32 Impurity: Not more than 0.7% Total Impurities: Not more than 1.0%
Assay
Not less than 99.0%
Loss on Drying
Not more than 1.0%
Residue On Ignition
Not more than 0.3%
7689-03-4
C20H16N2O4
348.352
Camptothecin inhibits DNA religation in the cleavage/religation step by binding to DNA topoisomerase I (topo I) and DNA which forms a DNA topoisomerase I - camptothecin - DNA complex. This complex causes DNA damage and leads to apoptosis.
2-8 °C
Camptotheca acuminata (plant)
RRT1.32 Impurity: Not more than 0.7% Total Impurities: Not more than 1.0%
Not less than 99.0%
Not more than 1.0%
Not more than 0.3%