CAS Number
7689-03-4
Molecular Formula
C20H16N2O4
Molecular Weight
348.352
Mechanism of Action
Camptothecin inhibits DNA religation in the cleavage/religation step by binding to DNA topoisomerase I (topo I) and DNA which forms a DNA topoisomerase I - camptothecin - DNA complex. This complex causes DNA damage and leads to apoptosis.
Storage Conditions
2-8 °C
Appearance
Light yellow crystalline powder
Source
Nothapodytes foetida
Impurity Profile
A:RRT0.90 Impurity: Not more than 0.3%
B:RRT1.45 Impurity: Not more than 0.5%
Total Impurities: Not more than 1.0%
Assay
Not less than 99.0%
Loss on Drying
Not more than 1.0%
Residue On Ignition
Not more than 0.3%
