Form
Powder
Appearance
Orange-red crystalline powder
Source
Streptomyces Peucetius
Impurity Profile
Impurity A| (8S,10S)-8-acetyl-10-[(3-amino-2,3,6-trideoxy-l-lyxo-hexopyranosyl)oxy]-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione (daunorubicin)|||| Impurity B| (8S,10S)-10[(3-amino-2,3,6-trideoxy-l-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione|||| Impurity C| (8S,10S)-10[(3-amino-2,3,6-trideoxy-l-lyxo-hexopyranosyl)oxy]-8-(bromoacetyl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione|||| Impurity D| (8S,10S)-6,8,10,11-tetrahydroxy-8-(hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione (doxorubicin aglycone, doxorubicinone)|
Water Content (Karl Fisher)
≤4.0%
pH
4.0-5.5
Melting Point
204-205°C
Assay
(On Dried Basis): 98.0-102.0%
