Spectinomycin is an aminocyclitol antibiotic similar to aminoglycosides.
TOKU-E offers two forms of spectinomycin: spectinomycin DiHCl (S006) and spectinomycin sulfate (S016). In aqueous solution, spectinomycin DiHCl is freely soluble, and spectinomycin sulfate is sparingly soluble (0.150 mg/mL).
CAS Number
64058-48-6
Molecular Formula
C14H26N2O11S•H2SO4•4H2O
Molecular Weight
502.49
Mechanism of Action
Aminocyclitols target the 30S ribosomal subunit resulting in an inability to read mRNA ultimately producing a faulty or nonexistent protein.
Storage Conditions
2-8°C
Tariff Code
2941.90.5000
Spectrum
Spectinomycin primarily targets gram negative bacteria, especially those which cause gonorrhea.
Form
Powder
Appearance
White or almost white powder
Source
Streptomyces sp.
Impurity Profile
Related Substances:
Impurity A,E (each): ≤1.0%
Impurity D: ≤4.0%
Any other impurity: ≤1.0%
Total impurities: ≤6.0%
Water Content (Karl Fisher)
12.0-16.5%
pH
3.8-5.6
Optical Rotation
+10.0° to +14.0°
Assay
(On Dried Basis): 93.0-102.0%
Sulfated Ash
≤ 1.0%
Endotoxin
≤ 0.17 IU/mg