Form
Powder
Appearance
Awhiteoralmostwhitepowder,hygroscopic.
Source
StreptomycesGriseus
ElementalAnalysis
Sulphate:18.0-21.5
Potency(onadrybasis)
≥720IU/mg
pH
4.5-7.0
LossonDrying
≤7.0%
Streptomycinsulfateisafreelysolubleaminoglycosideantibiotic.Streptomycincanbeusedincombinationwithpenicillintopreventcellculturecontamination.
3810-74-0
C21H39N7O12·1.5H2SO4
728.69
Aminoglycosidestargetthe30SribosomalsubunitresultinginaninABIlitytoreadmRNAultimatelyproducingafaultyornonexistentprotein.
2941.20.5000
StreptomycinsulfatetargetsprimarilyGrampositivebacteriaandMycobacterium.Interestingly,streptomycinhasbeenfoundtobeeffectiveagainstcertainβ-lactamsensitiveVREorvancomycinresistantEnterococcus;aglycopeptideantibioticresistant"superbug."
Powder
Awhiteoralmostwhitepowder,hygroscopic.
StreptomycesGriseus
Sulphate:18.0-21.5
≥720IU/mg
4.5-7.0
≤7.0%