Appearance
Almostwhiteorslightlyyellowpowder
pH
8.5-10.5
Assay
≥900IU/mg(ondriedbasis)
LossonDrying
≤5.0%
SulfatedAsh
≤3.0%
Impurities
Tyramine:≤3.5%
Tylosinisabroadspectrumbacteriostaticmacrolideantibioticandiscommonlyusedinveterinarymedicine.
1401-69-0
C46H77NO17
916.10
Macrolideantibioticsinhibitbacterialgrowthbytargetingthe50Sribosomalsubunitpreventingpeptidebondformationandtranslocationduringproteinsynthesis.Resistancetotylosiniscommonlyattributedtomutationsin50SrRNApreventingtylosinbindingallowingthecelltosynthesizeproteinsfreeoferror.
2941.90.1010
TylosintargetsprimarilygrampositivebacteriaandspeciesoftheMycoplasmagenus.
Almostwhiteorslightlyyellowpowder
8.5-10.5
≥900IU/mg(ondriedbasis)
≤5.0%
≤3.0%
Tyramine:≤3.5%