Prodigiosinisanintenselyredpyrrolepigmentproducedbyseveralbacteria,mostnotablySerratiamarcescens.Prodigiosinhasabroad
icalprofilewithactivityagainstfungi,tumorcelllinesandmalaria.Itwasshowntobeanimmunosuppressantin2007.
Prodigiosinis solublein ethanol,methanol,DMFandDMSO.
CASNumber
82-89-3
MolecularFormula
C20H25N3O
MolecularWeight
323.4
MechanismofAction
Prodigiosinactsviacaspaseinhibitiontoinduceofapoptosisinhumanprimarycancercells.Prodigiosinalsoactsasaninducerofp21WAF1/CIP1expressionviatransforminggrowthfactor-βreceptorpathway,andactivatesNAG-1viaglycogensynthasekinase-3β.
StorageConditions
-20°C