Quinomycin A is a cyclic depsipeptide metabolite. Quinomycin A has broad activity against bacteria, fungi and viruses, and has found application as an antitumor agent. Quinomycin A acts by bifunctional intercalation of nucleic acids. Recent research has shown quinomycin A to be an extremely potent inhibitor of hypoxia-inducible factor-1 (HIF-1). This transcription factor plays an essential role in tumor progression and metastasis.
Quinomycin A is soluble in DMF and DMSO and has limited solubility in ethanol and methanol.
CAS Number
512-64-1
Molecular Formula
C51H64N12O12S2
Molecular Weight
1101.3
Storage Conditions
-20°C
Specifications:
Appearance
Fawn to off-white solid