Trinactin is a member of the macrotetrolide complex produced by a range of Streptomyces sp.. Early literature reported that trinactin was a monovalent cation ionophore with high selectivity for ammonium and potassium. Trinactin has not previously been available for intensive investigation.
Trinactin is soluble in ethanol, methanol, DMF and DMSO.
CAS Number
7561-71-9
Molecular Formula
C43H70O12
Molecular Weight
779.0
Mechanism of Action
Trinactin inhibits T-cell proliferation induced by IL-2, and cytokine production at nanomolar levels for IL-2, IL-4, IL-5 and interferon-γ.
Storage Conditions
-20°C