Toxoflavin is a distinctive yellow pigment produced by some species of Pseudomonas and Streptomyces. Toxoflavin is one of two toxins produced when a fermented coconut drink, Tempe bonkrek, is contaminated with P. cocovenenans. Toxoflavin (PKF 118-310) is a potent antagonist of Tcf4/b-catenin signalling, inhibiting the expression of survivin and inducing apoptosis in several tumor cell lines.
Toxoflavin is soluble in ethanol, methanol, DMF and DMSO.
CAS Number
84-82-2
Molecular Formula
C7H7N5O2
Molecular Weight
193.2
Storage Conditions
-20°C
Specifications: