Miconazole is an imidazole antimycotic compound.
CAS Number
22916-47-8
Molecular Formula
C18H14Cl4N2O
Molecular Weight
416.13
Mechanism of Action
Miconazole increases cell permeability by inhibiting enzymes involved in ergosterol synthesis. The increase of permeability has a toxic effect on the fungi and leads to cell death.
Spectrum
Miconazole targets fungi that cause tinea (ringworm) especially Trichophyton species.
Form
Powder
Appearance
White or off white powder
Impurity Profile
Impurity C| (2RS)-2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethanamine||||
Melting Point
83°C - 87°C
Optical Rotation
-0.10° - +0.10°
Assay
99.0% - 101.0% (Dried basis)