Chlorotetracycline HCl, EP is tetracycline antibiotic and the first antibiotic of the tetracycline class to be discovered. Chlorotetracycline HCl is soluble at 8.6 mg/mL.
Chlortetracycline HCl, EP meets European Pharmacopoeia (EP) specifications.
64-72-2
C22H23ClN2O8· HCl
515.34 g/mol
The mechanism of chlorotetracycline involves entering a cell and binding to the 30s ribosomal subunit preventing peptide elongation and ultimately inhibiting protein synthesis. Resistance to chlorotetracycline can be a result of inactivation by cell enzymes or pumping the antibiotic out of the cell upon entering.
2941.30.0000
Chlorotetracycline is a broad spectrum antibiotic targeting a wide variety of gram positive and gram negative bacterial cells.
Powder
Yellow powder
Streptomyces aureofaciens.
≤2.0%
A460≤0.400
2.3-3.3
-235° to -250°
≤ 0.5%
≤50ppm
4-EPI CTC≤4.0%
CTC-HCl≥89.5% (dried basis)
TC-HCl≤8.0% (dried basis)
TC-HCl+CTC-HCl: 94.5-100.5% (dried basis)
