Violaceinisanintensevioletpigmentformedbythecondensationoftwotryptophanunits,foundinanumberofbacteria,notablyChromobacteriumviolaceum.TheregulationofpigmentbiosynthesisisthechromogenicbasisfortheuseofC.violaceumCV26forthedetectionofquorumsensingmediators.ViolaceincelltoxicityresemblesTNF-αsignaltransduction.
Violaceinissolubleinethanol,methanol,DMFandDMSO.
CASNumber
548-54-9
MolecularFormula
C20H13N3O3
MolecularWeight
343.3
MechanismofAction
Violaceinexhibitsbroadspectrumactivityagainstbacteria,protozoans(includingmalaria),virusesandmammaliancelllines.
StorageConditions
-20°C