FilipincomplexcomprisesafamilyofpentaenemacrocycliclactonesfirstisolatedfromStreptomycesfilipinensisandreportedbyresearchersatUpjohnin1955.Filipincomplexconsistsoffouranalogues,withfilipinIIIcomprisingthebulk(>70%)ofthecomplex.Filipincomplexisapotentbroadspectrumantifungalagentthatalsoexhibitsantitumorandantiviralactivities.Filipincomplexactsbybindingcellmembranesterols,disruptingmembraneintegrity.
Filipincomplexissolubleinethanol,methanol,DMForDMSO.
CASNumber
11078-21-0
MolecularFormula
C35H58O11(forFlipinIII)
MolecularWeight
654.8
StorageConditions
-20°C
Specifications: