Filipin complex comprises a family of pentaene macrocyclic lactones first isolated from Streptomyces filipinensis and reported by researchers at Upjohn in 1955. Filipin complex consists of four analogues, with filipin III comprising the bulk (>70%) of the complex. Filipin complex is a potent broad spectrum antifungal agent that also exhibits antitumor and antiviral activities. Filipin complex acts by binding cell membrane sterols, disrupting membrane integrity.
Filipin complex is soluble in ethanol, methanol, DMF or DMSO.
CAS Number
11078-21-0
Molecular Formula
C35H58O11 (for Flipin III)
Molecular Weight
654.8
Storage Conditions
-20°C