Form
Powder
Appearance
White or almost white crystalline powder
Source
Synthetic
Water Content (Karl Fisher)
Loss on drying: <0.5%
Melting Point
162 -166°C
Assay
(On Dried Basis): 98.5-101.0%
Econazole nitrate is an insoluble (0.00148 mg/mL) imidazole antifungal that specifically targets the cell membrane of fungi.
68797-31-9
C18H15Cl3N2O · HNO3
444.70
Econazole nitrate increases cell permeability by inhibiting enzymes involved in ergosterol synthesis. The increase of permeability has a toxic effect on the fungi and leads to cell death.
2-8°C
2933.29.4300
Econazole nitrate targets fungi responsible for tinea (ringworm) especially Trichophyton and Microsporum species.
Powder
White or almost white crystalline powder
Synthetic
Loss on drying: <0.5%
162 -166°C
(On Dried Basis): 98.5-101.0%