Form
Powder
Appearance
Yellowcrystallinepowder
Source
Streptomycespeucetius
WaterContent(KarlFisher)
1.4-2.8%
pH
2.0-3.0
Impurities
Methacycline:Notmorethan2.0%
6-epidoxycycline:Notmorethan2.0%
Otherimpurities:Notmorethan0.5%
Doxycyclinehyclateisasemisynthetictetracyclineantibioticandisfreelysolubleinaqueoussolution(50mg/mL).
24390-14-5
C22H24N2O8·HCl·0.5H2O·0.5C2H6O
512.94
Tetracyclinespassthecellmembraneandbindtothe30SribosomalsubunitinterferingwiththetRNA/mRNAinteractionandultimatelyinhibitingproteinsynthesis.
2-8°C
2941.30.0000
DoxycyclinehyclateisabroadspectrumantibioticprimarilytargetingbacteriaresponsIBLeforcausingrespiratoryinfectionsincludingMycoplasmapneumoniaeandHaemophilusinfluenzae.Doxycyclinehasbeenfoundtobeeffectiveagainstcertainβ-lactamresistantstrainsofVREorvancomycinresistantEnterococcus;aglycopeptideantibioticresistant"superbug."
Powder
Yellowcrystallinepowder
Streptomycespeucetius
1.4-2.8%
2.0-3.0
Methacycline:Notmorethan2.0%
6-epidoxycycline:Notmorethan2.0%
Otherimpurities:Notmorethan0.5%