Rifampicinisasparinglysoluble(1.4mg/mL)bacterialproteinsynthesisinhibitingantibiotic.
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CASNumber
13292-46-1
MolecularFormula
C43H58N4O12
MolecularWeight
822.94
MechanismofAction
RifampicintargetsprokaryoticDNAdependentRNApolymeraseswhichpreventsubsequentRNAtranscriptionandproteintranslation.
StorageConditions
Protectfromlightat-20°C.
TariffCode
2941.90.5000
Spectrum
Rifampicinisabroadspectrumantibiotictargetingawiderangeofgrampositive,gramnegative,andMycobacteriumspecies.
Form
Powder
Appearance
Brownish-redcrystallinepowder
Source
Semi-synthetic:AmycolatopsisRifamycinica
ImpurityProfile
RelatedSubstances:
RifampicinQuinone:≤1.5%
SinglePeak:≤1.0%
SumofPeaks:≤3.5%
pH
4.5-6.5
Density
≥0.7g/cc
Assay
(OnDriedBasis):97.0-102.0%
LossonDrying
≤1.0%
ResidueOnIgnition
≤0.1%
HeavyMetals
≤20ppm