Milbemycinsareacomplexfamilyofmacrocycliclactonescontainingahighlycharacteristicspiroketalgroup,producedbyStreptomyceshydroscopicussubsp.aureolarcrimosus.MilbemycinDisaminormemberofagroupofanaloguescontaininga25-isopropylsubstituent.MilbemycinDisahighlyselectiveandpotentnematocideandinsecticide.
Milbemycinsaresolubleinethanol,methanol,DMForDMSO.Poorwatersolubility.
CASNumber
77855-81-3
MolecularFormula
C33H48O7
MolecularWeight
556.7
MechanismofAction
Likethecloselyrelatedavermectin,milbemycinsarethoughttoactbyopeningglutamatesensitivechloridechannels.
StorageConditions
-20°C