Milbemycinsareacomplexfamilyofmacrocycliclactonescontainingahighlycharacteristicspiroketalgroup,producedbyStreptomyceshydroscopicussubsp.aureolarcrimosus.MilbemycinA4isthedominantmemberofagroupofanaloguescontaininga25-ethylsubstituent.MilbemycinA4isahighlyselectiveandpotentnematocideandinsecticide.
MilbemycinA4issolubleinethanol,methanol,DMForDMSO.Poorwatersolubility.
CASNumber
51596-11-3
MolecularFormula
C32H46O7
MolecularWeight
542.3
MechanismofAction
Likethecloselyrelatedavermectins,milbemycinsarethoughttoactbyopeningglutamatesensitivechloridechannels.
StorageConditions
-20°C