Form
Powder
Appearance
Whiteoroff-whitecrystallinepowder
Source
Synthetic
MeltingPoint
225-231°C
Assay
(OnDriedBasis):≥98.0%
LossonDrying
≤0.5%
Nalidixicacidisanaphthyridoneantibioticsimilarinstructureandmechanismtoquinolones.
TOKU-Eofferstwoformsofnalidixicacid: nalidixicacid(N011) andnalidixicacidsodiumsalt, CulturePure® (N001).Nalidixicacidissparinglysolubleinaqueoussolutionat0.1mg/mL.Nalidixicacidsodiumsaltisfreelysolubleinaqueoussolutionat50mg/mL.
389-08-2
C12H12N2O3
232.24
NalidixicacidindirectlyinhibitsproteinssynthesisbybindingDNAandinterferingwithenzymesinvolvedinDNAreplicationandtranscription.
2-8°C
2933.49.2600
NalidixicacidisabroadspectrumantibioticcommonlyusedagainstbacteriaresponsIBLeforurinarytractinfections.
Powder
Whiteoroff-whitecrystallinepowder
Synthetic
225-231°C
(OnDriedBasis):≥98.0%
≤0.5%