Milbemycinsareacomplexfamilyofmacrocycliclactonescontainingahighlycharacteristicspiroketalgroup,producedbyStreptomyceshydroscopicussubsp.aureolarcrimosus.MilbemycinA3isamajormemberofagroupofanaloguescontaininga25-methylsubstituent.MilbemycinA3isahighlyselectiveandpotentnematocideandinsecticide.
MilbemycinA3issolubleinethanol,methanol,DMForDMSO.Poorwatersolubility.
CASNumber
51596-10-2
MolecularFormula
C31H44O7
MolecularWeight
528.7
MechanismofAction
Likethecloselyrelatedavermectins,milbemycinsarethoughttoactbyopeningglutamatesensitivechloridechannels.
StorageConditions
-20°C