Vancomycin is a bactericidal glycopeptide antibiotic and has been used to treat infections caused by multi drug resistant bacteria including methicillin resistant Staphylococcus aureus (MRSA).
Vancomycin is freely soluble in water. Click here for more vancomycin products.
CAS Number
1404-90-6
Molecular Formula
C66H75Cl2N9O24
Molecular Weight
1449.25
Mechanism of Action
Vancomycin prevents peptidoglycan synthesis by two separate mechanisms. One mechanism prevents N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) from linking together forming the peptidoglycan backbone. The second mechanism prevents crosslinking between amino acid residues in the peptidoglycan chain.
Storage Conditions
2-8°C
Tariff Code
2941.90.1010
Spectrum
Vancomycin inhibits growth of many Gram positive bacteria including the antibiotic resistant superbug, MRSA (Methicillin resistant Staphylococcus aureus). Vancomcyin is effective for treating MRSA infections because it inhibits cell wall synthesis through a different mechanism than β-lactam antibiotics.
Form
Powder
Appearance
White to off-white powder
Source
Streptomyces orientalis
Impurity Profile
Individual Impurity: Not more than 3.0%
Related Substances: Not more than 7.0%
Content of EDTA: Not more than 120 ppm
Water Content (Karl Fisher)
Not more than 20.0%
Absorbance
(465nm): Not more than 0.1
Assay
(As Is): Not less than 850 µg/mg
(Dried Basis): Not less than 950 µg/mg
Residue On Ignition
Not more than 1.0%
Heavy Metals
Not more than 20 ppm