EprinomectinB1aisasemi-syntheticanalogueofavermectinB1apreparedbyoxidationofthe4""-hydroxymoietyandreductiveaminationfollowedbyacetylation.EprinomectinB1aisthemajorcomponent(>90%)ofthecommercialproductforendo-andexo-parasitecontrol,eprinomectin.Theavermectinsandmilbemycinsarealsopotentinsecticidesandacaricides.
EprinomectinB1aissolubleinethanol,methanol,DMForDMSO.Poorwatersolubility.
CASNumber
133305-88-1
MolecularFormula
C50H75NO14
MolecularWeight
914.1
MechanismofAction
Membersoftheavermectin/milbemycinclassexerttheiranthelminticeffectsbybindingtoglutamate-gatedchloridechannelsexpressedonnematodeneuronesandpharyngealmusclecells.
StorageConditions
-20°C