Form
Powder
Appearance
Whiteoryellowish-whitepowder
MeltingPoint
199°C-203°C
Assay
(OnDriedBasis):98.5-101.0%
LossonDrying
≤0.5%
ResidueOnIgnition
≤0.1%
Trimethoprimisabactericidaldihydrofolatereductaseinhibitor.
TOKU-Eofferstwoformsoftrimethoprim:trimethoprim(T011)andtrimethoprimlactate(T012).Trimethoprimhaslowsolubilityinaqueoussolution(0.4mg/mL).Trimethoprimlactateisfreelysolubleinaqueoussolution(19.6mg/mL).
738-70-5
C14H18N4O3
290.32
TrimethoprimpreventsbacteriafromtakingupfolicacidwhichisusedtosynthesizetheessentialDNAnucleotidethymine.
2-8°C
2933.59.2200
TrimethoprimisabroadspectrumantibioticusedextensivelyagainstbacteriaresponsIBLeforurinarytractinfections.
Powder
Whiteoryellowish-whitepowder
199°C-203°C
(OnDriedBasis):98.5-101.0%
≤0.5%
≤0.1%