Form
Powder
Appearance
White or yellowish-white powder
Melting Point
199°C-203°C
Assay
(On Dried Basis): 98.5-101.0%
Loss on Drying
≤0.5%
Residue On Ignition
≤0.1%
Trimethoprim is a bactericidal dihydrofolate reductase inhibitor.
TOKU-E offers two forms of trimethoprim: trimethoprim (T011) and trimethoprim lactate (T012). Trimethoprim has low solubility in aqueous solution (0.4 mg/mL). Trimethoprim lactate is freely soluble in aqueous solution (19.6 mg/mL).
738-70-5
C14H18N4O3
290.32
Trimethoprim prevents bacteria from taking up folic acid which is used to synthesize the essential DNA nucleotide thymine.
2-8 °C
2933.59.2200
Trimethoprim is a broad spectrum antibiotic used extensively against bacteria responsible for urinary tract infections.
Powder
White or yellowish-white powder
199°C-203°C
(On Dried Basis): 98.5-101.0%
≤0.5%
≤0.1%