Vancomycin HCl, USP is a bactericidal glycopeptide antibiotic and has been used to treat infections caused by multi drug resistant bacteria including methicillin resistant Staphylococcus aureus (MRSA).
Vancomycin HCl, USP is freely soluble in water. Click here for more vancomycin products.
CAS Number
1404-93-9
Molecular Formula
C66H75Cl2N9O24 · HCl
Molecular Weight
1485.71
Mechanism of Action
Vancomycin prevents peptidoglycan synthesis by two separate mechanisms. One mechanism prevents N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) from linking together forming the peptidoglycan backbone. The second mechanism prevents crosslinking between amino acid residues in the peptidoglycan chain.
Storage Conditions
2-8°C, protect from light
Tariff Code
2941.90.5000
Spectrum
Vancomycin inhibits growth of many Gram positive bacteria including the antibiotic resistant superbug, MRSA (Methicillin resistant Staphylococcus aureus). Vancomcyin is effective for treating MRSA infections because it inhibits cell wall synthesis through a different mechanism than β-lactam antibiotics.
Form
Powder
Appearance
White or light brown powder
Source
Streptomyces orientalis
Impurity Profile
Vancomycin B: Not less than 85%
Any Individual Impurity: Not more than 5.0%
Water Content (Karl Fisher)
Not more than 5.0%
pH
2.5 - 4.5
Assay
(Dried Basis): Not less than 900 μg/mg