Anguinomycin A, isolated from a Streptomyces sp., displays nanomolar cytotoxicity to murine P388 leukemia cells. In addition, it shows antitumor activity in vivo against murine Lewis lung carcinoma and P388 leukemia. Anguinomycin A is an analogue of leptomycin B, an inhibitor of nuclear export of proteins.
Anguinomycin A is soluble in ethanol and methanol (ethanol recommended). Unstable in DMSO.
CAS Number
111278-01-4
Molecular Formula
C31H44O6
Molecular Weight
512.7
Storage Conditions
-20°C
Specifications:
Appearance
Pale yellow film