Cytochalasin D is the most studied of the cytochalasins. Like most of the members of this mycotoxin class, cytochalasin D exhibits potent inhibition of actin filament function leading to cell death by apoptosis. This led to early investigation of the metabolite as an antitumor agent. Cytochalasin D has become one of the standard cellular probes for investigating the role of actin in cell biology.
Cytochalasin D is soluble in ethanol, methanol, DMF and DMSO.
CAS Number
22144-77-0
Molecular Formula
C30H37NO6
Molecular Weight
507.6
Mechanism of Action
Cytochalasin D exhibits potent inhibition of actin filament function leading to cell death by apoptosis.
Storage Conditions
-20°C