Bafilomycin C1 is a member of a potent family of macrocyclic lactones. Bafilomycin C1 is broadly active against bacteria, fungi, insects, nematodes and cestodes. Bafilomycin C1 has attracted interest as a potential agent for treating osteoporosis. The presence of the fumarate group provides an ideal ligand for affinity chromatography of V-ATPase.
Bafilomycin C1 is soluble ethanol, methanol, DMF and DMSO.
CAS Number
88979-61-7
Molecular Formula
C39H60O12
Molecular Weight
734.9
Mechanism of Action
Bafilomycin C1 is an inhibitor of vacuolar-type ATPase.
Storage Conditions
-20°C