Sparfloxacin is a synthetic fluoroquinolone antibiotic and is sparingly soluble in aqueous solution (0.113 mg/mL).
CAS Number
110871-86-8
Molecular Formula
C19H22F2N4O3
Molecular Weight
392.40
Mechanism of Action
Fluoroquinolone antibiotics target bacterial DNA gyrase, an enzyme which reduces DNA strain during replication. Because DNA gyrase is required during DNA replication, subsequent DNA synthesis and ultimately cell division is inhibited.
Storage Conditions
≤30°C
Tariff Code
2933.59.3600
Spectrum
Sparfloxacin is a broad spectrum antibiotic targeting a wide range of Gram positive, Gram negative, and Mycoplasma species especially those which cause pneumonia.
Form
Powder
Appearance
Yellow Crystalline Powder
Source
Synthetic
Impurity Profile
Related substances: Not more than 1.0%
Pyridine: Not more than 0.02%
Assay
(Dried Basis): 98.5-102.0%
Loss on Drying
Not more than 1.0%
Residue On Ignition
Not more than 0.2%
Heavy Metals
Not more than 0.002%
Residual Solvents
Toluene: Not more than 0.089%
Chloroform: Not more than 0.006%