Sparfloxacinisasyntheticfluoroquinoloneantibioticandissparinglysolubleinaqueoussolution(0.113mg/mL).
CASNumber
110871-86-8
MolecularFormula
C19H22F2N4O3
MolecularWeight
392.40
MechanismofAction
FluoroquinoloneantibioticstargetbacterialDNAgyrase,anenzymewhichreducesDNAstrainduringreplication.BecauseDNAgyraseisrequiredduringDNAreplication,subsequentDNAsynthesisandultimatelycelldivisionisinhibited.
StorageConditions
≤30°C
TariffCode
2933.59.3600
Spectrum
SparfloxacinisabroadspectrumantibiotictargetingawiderangeofGrampositive,Gramnegative,andMycoplasmaspeciesespeciallythosewhichcausepneumonia.
Form
Powder
Appearance
YellowCrystallinePowder
Source
Synthetic
ImpurityProfile
Relatedsubstances:Notmorethan1.0%
Pyridine:Notmorethan0.02%
Assay
(DriedBasis):98.5-102.0%
LossonDrying
Notmorethan1.0%
ResidueOnIgnition
Notmorethan0.2%
HeavyMetals
Notmorethan0.002%
ResidualSolvents
Toluene:Notmorethan0.089%
Chloroform:Notmorethan0.006%