Illudin S is potent antitumor sesquiterpene, first isolated from the fungus, Clitocybe illudens, in 1963. Illudin S is metabolically activated to reactive intermediates that bind DNA. The DNA damage appears to differ from that of other reactive metabolites. Importantly, illudin S exhibits in vitro and in vivo potency against multi-drug resistant tumors.
Illudin S is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
CAS Number
1149-99-1
Molecular Formula
C15H20O4
Molecular Weight
264.3
Storage Conditions
-20°C
Specifications:
Appearance
Light yellow solid