Appearance
White powder
Assay
90.0%
GE2270 is a thiopeptide antibiotic mixture isolated from Planobispora rosea. GE2270 consists of 10 different but closely related congeners that differ in their state of methylation.
C56H55N15O10S6
1289.26
GE2270 targets protein synthesis by inhibiting bacterial elongation factor Tu (EF-Tu) which prevents the transfer of aminoacyl-tRNAs to bacterial ribosomes.
GE2270 is active against malaria parasites, some human cancer cells, and Gram-positive bacteria including MRSA.
White powder
90.0%