Staurosporine is an unusual indolocarbazole alkaloid produced by a range of actinomycete species. It is a potent antitumor active, inducing apoptosis in a variety of cell lines. At submicromolar concentrations, staurosporine inhibits both IKKalpha and IKKbeta.
Staurosporine is soluble in ethanol, methanol, DMF and DMSO.
CAS Number
62996-74-1
Molecular Formula
C28H26N4O3
Molecular Weight
466.5
Mechanism of Action
Staurosporine is a potent inhibitor of many kinases including protein kinase C, tyrosine kinase, CDK2/cyclin A and CDK4/cyclin D.
Storage Conditions
-20°C