10'-Desmethoxystreptonigrin is a close analogue of streptonigrin produced by selected Streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. 10'-Desmethoxystreptonigrin has also been reported to have potent and broad spectrum antibacterial and antitumor activity.
10'-Desmethoxystreptonigrin is soluble in ethanol, methanol, DMF and DMSO.
CAS Number
136803-89-9
Molecular Formula
C24H20N4O7
Molecular Weight
476.1
Storage Conditions
-20°C
Specifications:
Appearance
Red Brown solid