Chaetocin is an epithiodioxopiperazine antibiotic that has recently shown promise as a selective antitumor agent. Chaetocin is dramatically accumulated in cancer cells via a process inhibited by glutathione. Inside the cell, its activity is mediated by the imposition of oxidative stress.
Chaetocin is soluble in ethanol, methanol, DMF and DMSO.
CAS Number
28097-03-2
Molecular Formula
C30H28N6O6S4
Molecular Weight
696.9
Mechanism of Action
Chaetocin is an inhibitor of lysine-specific methyltransferase SU(VAR)3-9 both in vitro and in vivo.
Storage Conditions
-20°C