ZaragozicacidAisthemajormetaboliteofaclassofunusualbicyclictricarboxylicacids,producedbyanumberoffungiinthegeneraCurvularia,Ex
SEROhilum,Setosphaeriaandothers,discoveredat
MerckandGlaxointheearly1990s.ZaragozicacidAispresentedasthefreeacidratherthanthetri-sodiumsalttoavoidst
ABIlityproblemsassociatedwithhydrolysisofthesalt.
ZaragozicacidAissolubleinethanol,methanol,DMFandDMSO.
CASNumber
142561-96-4
MolecularFormula
C35H46O14
MolecularWeight
690.7
MechanismofAction
ZaragozicacidAisaninhibitorofsqualenesynthase,anenzymeinvolvedinsterolbiosynthesis.
StorageConditions
-20°C
Specifications:
Appearance
Whitetolighttansolid