Cefditoren pivoxil is a third generation cephalosporin antibiotic.
TOKU-E offers three forms of cefditoren: cefditoren (C100), cefditoren sodium (C094), and cefditoren pivoxil (C050). Cefditoren sodium is soluble in aqueous solution, and cefditoren pivoxil is soluble in fat.
117467-28-4
C25H28N6O7S3
620.72 g/mol
Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases.
-20°C
2941.90.5000
Cefditoren is a broad spectrum antibiotic commonly used against bacteria responsible for community acquired pneumonia and pharyngitis
Powder
Light yellow or off-white crystalline powder
≤1.5%
-45° - -52°
944-1005 µg/mg (on dried basis)
≤0.2%
≤10 ppm
Single Impurity: ≤0.1%
Total Impurities: ≤5.0%
